Bij orthopedische prothesiologie – die niet in dagopname gebeuren – wordt in veel ziekenhuizen een profylactische AB dekking van 24 uur gegeven. Dat wil zeggen 1 gift pre operatief en 2 giften postoperatief (8 en 16 uur na de operatie).
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Literatuur: - Vancomycin Prophylaxis for Total Joint Arthroplasty: Incorrectly Dosed and Has a Higher Rate of Periprosthetic Infection Than Cefazolin
- Single-Dose Perioperative Antibiotics Do Not Increase the Risk of Surgical Site Infection in Unicompartmental Knee Arthroplasty
- Similar risk of complete revision for infection with single-dose versus multiple-dose antibiotic prophylaxis in primary arthroplasty of the hip and knee
- Perioperative Antibiotic Prophylaxis in Total Joint Arthroplasty
- Is There a Difference in Infection Risk Between Single and Multiple Doses of Prophylactic Antibiotics? A Meta-analysis
- Efficacy of A Single Dose of Cefazolin as a Prophylactic Antibiotic in Primary Arthroplasty
- Dual Antibiotic Prophylaxis in Primary Total Knee Arthroplasty—No Benefit for Extremely Obese Patients
- Changing antibiotic prophylaxis for primary joint arthroplasty affects postoperative complication rates and bacterial spectrum
- Cefazolin Prophylaxis for Total Joint Arthroplasty: Obese Patients Are Frequently Underdosed and at Increased Risk of Periprosthetic Joint Infection
- Increased risk of prosthetic joint infection following primary total knee and hip arthroplasty with the use of alternative antibiotics to cefazolin